To rescue Ashley in Chapter 13 of the Resident Evil 4 Remake, players must track down the Wrench to upgrade their laboratory keycard. Upgrading the keycard involves entering a gauntlet of hostile bioweapons, searching for the right tools, and solving some of Resident Evil’s notoriously tricky puzzles. The Wrench is essential to getting the Level 3 Keycard Upgrade, but players may have trouble finding it without searching in a rather unexpected location.

https://screenrant.com/where-to-find-wrench-location-resident-evil-4-remake/