Led by Fran Drescher's Fran Fine, The Nanny cast is composed of veteran actors from both television and film. The classic '90s sitcom The Nanny aired for six seasons and over 140 episodes on CBS between 1993 and 1999. It was the show that made star Fran Drescher a household name. Co-created with her then-husband Peter Marc Jacobson, The Nanny was partly inspired by a trip Drescher took to London to visit her former Princesses co-star Twiggy. After spending a lot of time with the British model-actress' kids, Drescher got the idea for a show riffing on The Sound Of Music but with her as a nanny instead of some Julie Andrews type.