It has been a long time since one star of The Conners had a cameo in a long-running animated sitcom, but the Roseanne spinoff clearly remembers this iconic appearance. During Roseanne's peak, the show was one of the most popular sitcoms on network television. However, even this working-class family sitcom struggled to match the global success of The Simpsons. The Simpsons was a pop culture juggernaut throughout the ‘90s, reshaping the landscape of television comedy, inspiring imitators as famous as South Park and Family Guy, and shifting millions of tons of merchandise. In contrast, Roseanne was just a hit sitcom.

https://screenrant.com/the-conners-season-6-sara-gilbert-simpsons-joke-explained/