The remake of Resident Evil 4 tweaks, refines, and overhauls some of the details of the original story, but one Easter egg implies a whole new background for one of its major characters. The original Resident Evil 4 left many questions unanswered, including Krauser's motivation for attacking Leon, and what exactly Ada was doing in Spain. While many of them were answered in other releases, the lack of clarity in the original Resident Evil 4 somewhat weakened its story.

https://screenrant.com/resident-evil-4-remake-easter-egg-luis-nemesis/