Audiences will return to the desolate wasteland of I Am Legend in a highly anticipated sequel, and some exciting actors have already joined the I Am Legend 2 cast. Set in a post-apocalyptic future, I Am Legend takes place in a world where an airborne cure for cancer killed 99% of the world’s population and turned everyone else into vampiric mutants known as “Darkseekers.” Will Smith stars as Dr. Robert Neville, the last man on Earth (or so it seems), determined to use his scientific know-how to figure out a way to save humanity. Now, Smith is returning for a long-awaited sequel to I Am Legend.