Icons Unearthed: Marvel creator and director credits Blade II with helping the Marvel Cinematic Universe discover its signature blend of humor and action. Blade II was the 2002 followup to 1998’s Blade, and is largely regarded to be the superior film. Those who aren’t familiar with the franchise may be surprised to learn that Blade II was directed by none other than Guillermo Del Toro, who is said to have taken everything good about the first Blade and turned it up a notch for the sequel.
https://screenrant.com/blade-2-laid-groundwork-mcu-humor-how/