While it would be atypical of the franchise to do so, it could benefit Grand Theft Auto 6 to bring in some of Grand Theft Auto 5's characters, as they might be too big to ignore. Every player is entitled to their own favorite characters in the franchise, but the triple protagonists of GTA 5 have undoubtedly left one of the biggest collective marks on the series. They've had such an impact on players, it begs the question if GTA 6 can get away with not including them without it being detrimental to the game.

https://screenrant.com/gta-6-ignore-5-characters-franklin-michael-trevor/