Doctor Strange has been through many traumatic experiences in the MCU, but there is one less-considered aspect of his arc that means he endures a much worse version of Thanos' "curse" laid out in Avengers: Infinity War. Doctor Strange and Thanos' interactions on Titan were a chance for Thanos to detail his motives before the epic Battle of Titan ensued. During that fight, as Thanos fought Tony, Thanos revealed his familiarity with Stark and that they shared a commonality: being "cursed with knowledge." Thanos saw Tony as an equal at this moment, while belittling Doctor Strange's powers as the "tricks" of a wizard, seemingly unaware of Strange's similar burden.

https://screenrant.com/doctor-strange-iron-man-thanos-curse-worse/