Tammy Slaton has lost 500 pounds since the premiere of 1000-lb Sisters, and her body has changed dramatically. When Tammy made her television debut in 2020, she weighed over 600 pounds, and her mobility was limited. She could barely walk, so she traveled around in a wheelchair, and she couldn’t even stand up for more than a few seconds without a walker. Tammy wouldn’t fit in a regular car seat, so she had to be driven around in a specialty van with its seats ripped out so she could recline on the floor. She had no independence and needed help with basic daily activities like bathing or feeding herself. Things would only get worse as Tammy went on to gain even more weight, getting up to 720 pounds at her heaviest.