Miguel O'Hara's Spider-Man 2099 is very different to the other Spider-People introduced in Spider-Man: Across the Spider-Verse, raising questions about whether he may be a vampire. Separate from his role of Moon Knight in the MCU, Oscar Isaac first voiced Miguel O'Hara at the end of Sony's 2018 animated adventure Spider-Man: Into the Spider-Verse, before being given a more pivotal role in the 2023 sequel. As the leader of the Spider Society, a group of interdimensional Spider-People tasked with protecting the stability of the multiverse, Miguel O'Hara's Spider-Man 2099 has a huge amount of power. However, he is isolated from other wall-crawlers, as he has a very different origin story.
https://screenrant.com/miguel-spider-man-2099-vampire-origin/