The return of Johnny Depp in Pirates of the Caribbean 6 is still up in the air, but if the actor chooses not to reprise the role of Jack Sparrow, the film could still focus on these 10 story ideas. Throughout the franchise's five films, the world of Pirates of the Caribbean has gotten much bigger than Jack Sparrow, with all kinds of lore and side characters filling up the universe. Because of this, there is tons of potential for stories that don't center on Johnny Depp, meaning that if he chooses not to return, Pirates of the Caribbean 6 could be about these potential storylines.
https://screenrant.com/pirates-caribbean-6-story-ideas-no-johnny-depp-jack-sparrow/