By making Netflix's Defenders Saga canon to the MCU, Marvel Studios may have also confirmed the canon status of Marvel Television's Agents of SHIELD. Since Marvel Studios began to develop its own long-form TV shows for Disney+, the canonicity of Marvel Television's previous shows has been called into question. Despite originally being thought to be set in the world of the MCU, popular series such as Agents of SHIELD, Daredevil, Jessica Jones, Luke Cage, Iron Fist, The Punisher and The Defenders were never referenced in Marvel Studios' theatrical releases, but it now seems as though the tide may be changing.

https://screenrant.com/mcu-defenders-update-agents-of-shield-canon-more-likely/