The influence of Gene Roddenberry's Star Trek on Seth MacFarlane's The Orville is well-documented, but it's far from the only piece of science fiction referenced in the sci-fi comedy-drama. First airing in 2017, The Orville was borne out of MacFarlane's desire to fill the gap in the TV schedules left by the cancelation of Star Trek: Enterprise way back in 2005. The series has featured many figures from Star Trek history both in front of and behind the cameras, and has liberally drawn from the Trek canon for some of its best moments.
https://screenrant.com/orville-sci-fi-franchise-references-easter-eggs/