Insomniac Games' Marvel's Spider-Man 2 is the latest in a series of video games that has done a phenomenal job of including a vast range of powerful adversaries for Peter Parker and Miles Morales to face – both universally known enemies and those that are little recognized outside the most dedicated Spider-Man fans. Despite this, there are a significant number of enemies that absolutely must feature in the inevitable sequel to the latest entry, Marvel's Spider-Man 2 – a few of whom have never made it into a game, but absolutely have the potential to be devastatingly powerful bosses that torment both Peter and Miles as well as New York.
https://screenrant.com/marvels-spider-man-2-sequel-villains/